BiOptimizers MassZymes Reviews: Will It Improve Your Digestive Health?

MassZymes is an all-natural supplement rich in digestive enzymes which boost overall gut health, improve energy levels, sharpen mental focus, and more.

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In This Review

What is MassZymes?

MassZymes is one of the many digestive health supplements on the market, and the formula focuses on enzymes which help break down food and boost nutrient absorption. It promises other benefits like sharpening mental clarity and focus, boosting energy levels, and speeding up muscle recovery.

MassZymes is an all-natural formula free of harmful additives, soy, and diary, and it’s suitable for both vegetarian and vegan diets. Let’s look at the details, and we’ll give you our honest opinion of the formula.

How Does MassZymes Rate?

Overall Rating: 3.7


Value for Cost

3.8/5Value for Cost



Brand Highlights

  • MassZymes contains 100% organically sourced ingredients.
  • The formula is free of dairy and soy.
  • MassZymes is suitable for vegetarian and vegan diets.
  • The manufacturing takes place in a GMP-certified facility in the USA.


morning kick

*All individuals are unique. Your results can and will vary.

Key Ingredients

  • Protease
  • Amylase
  • Lipase
  • Bromelain
  • Lactase
  • Invertase
  • Diastase
  • Glucoamylase
  • Alpha-Galactosidase


  • MassZymes may support healthy digestion.
  • This supplement could improve mental clarity and focus.
  • MassZymes might boost energy levels.
  • The product may speed up muscle recovery.
  • MassZymes might boost nutrient absorption.


  • MassZymes is an expensive supplement for the market.
  • The recommended dosage is 9 capsules daily, which may be difficult for some people.
  • The supplement may initially cause digestive upset for a day or two.

You can BUY it directly from the Official Website

Who is the Manufacturer of MassZymes?

The manufacturer of the MassZymes supplement is a company called BiOptimizers, which has its headquarters in Reno, Nevada.

Founded in 2004, they have almost 20 years of experience developing health and wellness supplements for a range of issues like digestion, brain health, sleep, and nutrition.

How Does MassZymes Work?

MassZymes BiOptimizers contains 100,000 units of enzymes in every capsule which digest proteins, starches, sugars, fats, and fiber for healthier, more regular bowel movements and ease of symptoms like gas, bloating, diarrhea, and constipation.

A chapter in the book Principles of Medical Biochemistry by Gerhard Meisenberg and Simmons discussed the structure, function, and properties of digestive enzymes in detail [1].

Not only do the enzymes boost overall digestive health, but they also maximize nutrient absorption for optimal health and immune functioning. This could help suppress appetite for possible weight loss over time, and enhanced gut health may improve energy levels.

The enzymes also help enhance healing in the body, which can speed up muscle recovery by repairing the damage. They decrease inflammation, which can improve the symptoms of leaky gut and other issues.

A review in Current Drug Metabolism by Gianluca Ianiro, et al explored the research on the use of digestive enzyme supplementation for gastrointestinal diseases [2].

Digestive enzymes could also have a positive impact on skin health, by decreasing inflammation and redness as well as possibly offering some anti-aging benefits.

The improved digestive health may also help clear up brain fog and enhance mental focus.

An article in the Annals of Gastroenterology by Marilia Carabotti, and Annunziata Scirocco, et al discussed the gut brain axis, the complex interaction between the microbiota and the central nervous system [3].

MassZymes Ingredients - Are They Safe & Effective?

These are some of the primary active MassZymes ingredients:


This is an enzyme produced in the pancreas and salivary glands, and it helps in the digestion of carbohydrates – turning starches into simple sugars. It supports healthy digestive function, reduces inflammation, and strengthens the immune system, we discussed in our ActivatedYou Active Enzyme Review.

A review published in Starch by Peter J. ButterworthFrederick J. Warren, and Peter R. Ellis discussed the connection between human amylase and starch digestion [4].

MassZymes Supplement Facts

MassZymes Supplement Facts


Bromelain is a proteolytic enzyme derived from pineapple juice which helps to digest protein, for improved digestion.

It contains potent anti-inflammatory agents which can decrease gut swelling as well as reduce joint and muscle pain. It also has benefits for healing wounds and burns.

A review by Rajendra Pavan, Sapna Jain, Shraddha, and Ajay Kumar published in Biotechnology and Research International examined the properties and therapeutic applications of bromelain [5].

In our comprehensive article on plexus ease reviews, we thoroughly documented the presence of this ingredient and provided detailed insights and analysis.


This is an enzyme that aids in the digestion of fats, and it exists both in your gut and in your salivary glands. It improves digestive health and can relieve symptoms like gas, bloating, and diarrhea. It may have some healing benefits for irritable bowel syndrome.

A review published in the Journal of Molecular Catalysis B: Enzymatic by Manjari Mukherjee discussed the role of metabolic lipases in human digestion [6].


ProPlant Complete Shake

*All individuals are unique. Your results can and will vary.

You can BUY it directly from the Official Website

Frequently Asked Questions (FAQs)

Q: How Do You Take It?

A: The recommended dosage is either 3 capsules with each meal or 1 capsule with each meal and 1-2 capsules between meals. Do not take more than the maximum daily dosage under any circumstances.

Q: What is the Return Policy of MassZymes?

A: The manufacturer is offering a 365-day satisfaction guarantee, but only for unopened bottles. if you bought multiple bottles, you could send back one open. Contact customer service for instructions and return the bottles within a year of the purchase. Your refund will exclude shipping and handling charges.

Q: Does MassZymes Work?

A: The combination of enzymes included in MassZymes BiOptimizers should have some impact on improving digestive health, and there’s research to support that. However, the customer reviews for the supplement offered mixed opinions, with some saying it worked and others mentioning that it had little impact.

Q: Where to Buy MassZymes?

A: You can purchase MassZymes on the manufacturer’s website, and it’s also available from a wide range of online retailers and stores like Amazon, Walmart, and pharmacies.

On the official site, you get free shipping for orders over $90. There are bonus gifts for purchases over $150 and over $400. You can make a one-time purchase, or you can subscribe to save 12%. The prices are as follows:

  • 1 Bottle – $66
  • 3 Bottles – $164
  • 5 Bottles – $255

Q: What Sets It Apart From the Competition?

A: MassZymes is a fairly typical organic digestive enzyme supplement and a little on the expensive side. What sets it apart is the fact that the product is suitable for vegetarians and vegans, which is not true of every brand.

What Do the MassZymes Reviews Say?

The MassZymes review postings varied quite a bit, with some users saying the product worked incredibly well to improve their digestion and others claiming it did very little or nothing.

Some customers found the supplement to be too expensive, while others said it was worth the cost. Here are a few of the user comments, to give you some idea of the feedback on MassZymes:

This Product is Amazing!

MassZymes works so well for helping me digest my food, eliminates bloating!~Amazon customer

Best on the Market?

Consider looking up MassZymes on YouTube before purchasing. The owner has some great videos. This formulation also works as a “systemic enzyme” which means you can take it on an empty stomach a few hours before eating in the morning and the enzymes will clean out undigested protein from your intestinal tract.

I purchased this on here after hearing about the product in a human garage. And noticed that buying from the Bioptimizer's website would be very expensive for somebody in Canada. So before committing, I tried this smaller bottle. The only thing that would make this product better is if the seller sold the 250 capsule bottles.~Zack, Amazon customer

Do Not Notice a Benefit

Easy to take. Did not notice a difference. Will not buy it again.~PK, Amazon customer


morning complete

*All individuals are unique. Your results can and will vary.

MassZymes Reviews - Conclusion

MassZymes is an all-natural supplement that supports digestive health by providing a number of key enzymes for better food breakdown, easier bowel movements, and ease of issues like bloating and diarrhea. It also promises to improve energy, speed muscle recovery, and boost mental focus. The product is somewhat expensive for the market.

The customer reviews for MassZymes was not clear cut, with the customer experience varying from person to person. Some found the supplement very helpful for digestion, energy, and other aspects of health, while others said it did little and was a waste of money.

BiOptimizers MassZymes includes only organic ingredients, with no artificial or synthetic additives or fillers, soy, or dairy. While not associated with many MassZymes side effects, there’s always a chance they could occur. We recommend that you check with a physician before starting this product.

Where To Find It?

You can BUY it directly from the Official Website

Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of Exclusive Best Offer. We do not verify or endorse any claims made in these reviews. Please read the full product reviews disclaimer. *All individuals are unique. Your results can and will vary.

Customer Reviews for MassZymes

BiOptimizers MassZymes Reviews: Will It Improve Your Digestive Health?

Customer Reviews & Ratings

3.0 out of 5

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  1. Selia

    Not fully satisfied!
    MassZymes claims to support digestion and nutrient absorption as it contains a blend of enzymes aimed at assisting the breakdown of proteins along with an array of digestive enzymes. I have been using it for two weeks and have yet to see major changes, but to some extent, it did work.

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250 Capsules
Protease, Amylase, Lipase, Bromelain, Lactase, Invertase, Diastase, Glucoamylase, Alpha-Galactosidase.

6 sources

We review published medical research in respected scientific journals to arrive at our conclusions about a product or health topic. This ensures the highest standard of scientific accuracy.

[2] Digestive Enzyme Supplementation in Gastrointestinal Diseases - PMC (
[3] The Gut-Brain Axis: Interactions Between Enteric Microbiota, Central And Enteric Nervous Systems - PMC (
[4] Human ?-Amylase And Starch Digestion: An Interesting Marriage:
[5] Properties and Therapeutic Application of Bromelain: A Review:
[6] Human Digestive And Metabolic Lipases—A Brief Review:

**This is a subjective assessment based on the strength of the available informations and our estimation of efficacy.

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