SkinCeuticals Metacell Renewal B3 Reviews - Is It Legit?

Metacell Renewal B3 is a natural anti-aging lotion which promises to tighten the skin, smooth lines and wrinkles, hydrate, and improve the overall health.

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In This Review

What is SkinCeuticals Metacell Renewal B3?

Metacell Renewal B3 by SkinCeuticals is an organic lotion with anti-aging benefits. It aims to boost skin health and hydration, and tighten the skin to smooth wrinkles and fine lines. This formula may also improve tone, repair damage, and heal skin conditions.

The lotion includes some quality, science-backed ingredients, and claims to be suitable for all skin types. Metacell Renewal B3 is a very expensive product for the market.

How Does It Rate?

Overall Rating: 3.5
Metacell Renewal B3Metacell Renewal B3


Value for Cost

3.0/5Value for Cost

Customer Reviews

3.6/5Customer Reviews

Brand Highlights

  • The formula includes only organic ingredients.
  • According to the manufacturer it’s suitable for all skin types, including sensitive.
  • There is some scientific evidence supporting the ingredients.
  • SkinCeuticals is not a cruelty-free brand.


Beverly Hills MD Deep Wrinkle Filler

*All individuals are unique. Your results can and will vary.

Key Ingredients

  • Niacinamide
  • Glycerin
  • Tri-Peptide Concentrate
  • Adenosine
  • Bitter Orange Flower Oil
  • Citrus Aurantium Amara Flower Oil
  • Limonene
  • Laminaria Digitata Extract
  • Pelargonium Graveolens Flower Oil
  • Cymbopogon Flexuosus Oil


  • Metacell Renewal B3 could tighten the skin and improve elasticity.
  • This formula may smooth fine lines and wrinkles.
  • SkinCeuticals Metacell Renewal B3 might hydrate the complexion.
  • It could diminish skin discoloration.
  • This lotion may improve skin cell turnover.


  • This is an extremely expensive skin care product.
  • Some users may develop an allergic skin reaction.
  • SkinCeuticals Metacell Renewal B3 Emulsion works better for some users than others.

How Does It Work?

This anti-aging formula includes peptides and other collagen and elastin-boosting ingredients which may tighten the skin, improve elasticity, and smooth wrinkles and fine lines.

A review in the Journal of Drugs and Dermatology discussed the role of collagen and elastin in cutaneous aging [1]. It includes anti-inflammatory properties which may reduce swelling and redness, and help heal some skin conditions.

The formula has hydrating substances which moisturize and prevent dryness, and may plump the complexion to further smooth lines and wrinkles. According to the Journal of the American Academy of Dermatology, moisturizers may be effective in healing dry skin [2].

Metacell Renewal B3 is high in antioxidants, which may get rid of some of the damaging free radicals on your skin and lower levels of oxidative stress.

This may boost the skin’s overall immunity, repair and heal the skin barrier, and protect from environmental threats like UV rays. An article in Plastic and Reconstructive Surgery discussed the importance of antioxidants in skin care [3].

Metacell Renewal B3 Ingredients - Are they Safe & Effective?

These are some of the primary active Metacell Renewal B3 ingredients:


- This form of Vitamin B3 provides hydration to the skin, and in particular works to strengthen and restore the skin barrier and keep in moisture. An article in the Journal of Cosmetic Dermatology discussed niacinamide and its potential skin benefits [4].

It brightens the complexion, repairs skin and damage, and offers anti-aging benefits. As mentioned in our Dark Spot Corrector reviews article, Niacinamide could reduce wrinkles and lines, improve skin tone, and boost cellular energy for overall better skin health.

A review in Antioxidants examined the research for the potential benefits of niacinamide in anti-aging and pigmentation [5].

Tri Peptide Concentrate

- Peptides are long strings of amino acids which synthesize proteins like collagen, and this formula promises 3 different strains. They tighten the skin, smoothing signs of age like fine lines and wrinkles.

A study in the International Journal of Cosmetic Sciences concluded that a collagen tripeptide had anti-aging benefits for the skin [6].

Peptides also have antioxidant and anti-inflammatory potential, and can heal skin damage, protect from further harm, and decrease redness and swelling.


- This is a highly hydrating organic compound which usually comes from vegetable oil. It has rich moisturizing benefits, and may eliminate dryness and plump the skin to smooth wrinkles and fine lines.

It may also strengthen the skin barrier and keep in moisture. A study in Scientific Reports explored the moisture retention benefits of different glycerin solutions [7]. Glycerin has antioxidant and anti-inflammatory properties, and may help heal some skin conditions.


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*All individuals are unique. Your results can and will vary.

SkinCeuticals Metacell Renewal B3 FAQ's

Q: How Do You Apply It?

A: You can use this formula twice a day, morning and evening, as part of your regular skin care routine. Take 2 pumps of the lotion and spread it evenly over your face, neck, and chest.

Q: What is the Return Policy?

A: SkinCeuticals has a 30-day return policy for their products. If you are not happy with the purchase, contact the company for instructions and send back the order within 30 days. You should get a full refund.

Q: Is It Worth It?

A: Metacell Renewal B3 includes some quality ingredients which may make it effective for some users, although the reviews varied. It is very costly for the market. Some may find it worth it, but others may choose to seek out a quality anti-aging formula which is cheaper.

Q: Where to Buy It?

A: Metacell Renewal B3 is for sale on the SkinCeuticals website, and from numerous other online and offline retailers. On the official site, the price for a one-time purchase is $120. If you subscribe to the monthly service, you save 5%.

Q: What Sets It Apart From the Competition?

A: The formula has some potency, especially with the tri-peptide formulation, but this doesn’t necessarily make it wildly different from other anti-aging lotions. Mostly what sets Metacell Renewal B3 apart from other brands is the high price.

SkinCeuticals Metacell Renewal B3 Reviews from Customers

Many of the SkinCeuticals Metacell Renewal B3 reviews had good things to say about the brand, citing effective anti-aging and other skin health benefits.

However, some customers found it less beneficial, and several said it was simply too costly to keep buying. Here are a selection of reviews, to give you some idea of the feedback.

Disappointing Packaging!

The product is excellent. Use it continually for skin care. However, do not like the packaging. The opaque bottle does not allow you to see when you are out of product.

Really wish Skinceuticals would change to a clear bottle so the buyer would know when they are running low on product. –Amazon Customer

Love This Product!

Been using this product for the past 6 weeks and could tell a difference within a week. Skin is baby soft and smooth. Use on face, neck and décolleté. –Amazon Customer

No Difference!

Honestly not sure of the good reviews. Been using over three months and really do not see any difference at all. – F. C


Beverly Hills MD Deep Wrinkle Filler

*All individuals are unique. Your results can and will vary.

SkinCeuticals Metacell Renewal B3 - Final Verdict

Metacell Renewal B3 is an anti-aging lotion which promises to moisturize dry skin, tone, tighten, improve elasticity, and smooth signs of age like wrinkles and fine lines. While it may offer benefits to some users, it comes at a high price tag.

There were a number of Metacell Renewal B3 reviews which had good comments about the cream, saying it did boost their skin health, remove lines, and provide a younger appearance. Other noticed few results and were not happy with the Metacell Renewal B3 before and after.

This formula contains pure organically sourced ingredients, and is free of chemical or synthetic additives. While it’s primarily safe, some users may develop a skin reaction due to an ingredient allergy. If this occurs, stop using the lotion.

There are several products of the same category available in the market like SkinCeuticals Serum 10 AOX+. However, choose wisely before trying out any products.

As we age the composition, texture and appearance of our skin changes. Signs of skin aging include wrinkles, fine lines, loss of moisture, uneven tone, and dull, tired-looking skin. There are countless anti-wrinkle creams on the market promising to make skin look and feel younger. Many anti-wrinkle creams promise everything short of a facelift or to provide the much sought after "fountain of youth". In reality most are just moisturizers marketed as anti-aging products.

Below you’ll find some of the most effective wrinkle serum/cream formulations on the market today, in our opinion.

Our Top Anti Wrinkle Serums Choices

Verdict on Claimed Benefits: Below is our summary of the available evidence for the claimed benefits of below mentioned anti-wrinkle serums based on the available research:

DRMTLGY Needless Serum | Organic Anti-Aging Skincare
Strengthens the Skin's Moisture Barrier*Gold Star Evidence
Targets the Appearance of Fine Lines & Wrinkles*Gold Star Evidence
Helps to Improve Skin Tone & Reduce the Dark Spots*Gold Star Evidence
Firms and Tightens the Skin, Improving Elasticity*Strong Evidence
Rating Breakdown
Support for Claims:
Ingredient Safety:
Value for the Price:
Brand Transparency:
Overall Rating: 4.9
Beverly Hill MD Wrinkle Repair Night Treatment | Overnight Repair Formula
Hydrates the Skin Overnight & Replenishes Moisture*Gold Star Evidence
Encourages Skin Cell Turnover and Renewal*Strong Evidence
Minimize the Appearance of Wrinkles & Promote Skin Renewal*Gold Star Evidence
Provides Skin Firmness and Elasticity*Strong Evidence
Rating Breakdown
Support for Claims:
Ingredient Safety:
Value for the Price:
Brand Transparency:
Overall Rating: 4.8
Beverly Hills MD Line Smoothing Serum
Reduce The Appearance of Fine Lines & Wrinkles*Gold Star Evidence
Support The Skin's Structural Foundation & Elasticity*Strong Evidence
Powerful Collagen-supporting Peptides Moisture-rich Volumizers*Strong Evidence
Promotes Youthful Skin*Strong Evidence
Rating Breakdown
Support for Claims:
Ingredient Safety:
Value for the Price:
Brand Transparency:
Overall Rating: 4.8

Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of Exclusive Best Offer. We do not verify or endorse any claims made in these reviews. Please read the full product reviews disclaimer. *All individuals are unique. Your results can and will vary.

Customer Reviews for SkinCeuticals Metacell Renewal B3

SkinCeuticals Metacell Renewal B3 Reviews - Is It Legit?

Customer Reviews & Ratings

3.0 out of 5

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  1. lisa H.

    Good but not properly sealed
    I frequently order this SkinCeuticals Metacell Renewal B3 product since I like it so much. The fact that the box arrived dented and with the top seal broken is the only problem I have with this order.

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SkinCeuticals Metacell Renewal B3
1.7 Ounce
Niacinamide, Glycerin, Tri-Peptide Concentrate, Adenosine, Bitter Orange Flower Oil, Citrus Aurantium Amara Flower Oil Limonene, Laminaria Digitata Extract, Pelargonium Graveolens Flower Oil, and Cymbopogon Flexuosus Oil.

12 Sources

We review published medical research in respected scientific journals to arrive at our conclusions about a product or health topic. This ensures the highest standard of scientific accuracy.

[1] Uitto J. The role of elastin and collagen in cutaneous aging: intrinsic aging versus photoexposure. J Drugs Dermatol. 2008 Feb;7(2 Suppl):s12-6. PMID: 18404866.
[2] Skin Moisturizers: Therapeutic Potential And Preventative Maintenance Of Dry Skin:
[3] Graf, Jeannette M.D.. Antioxidants and Skin Care: The Essentials. Plastic and Reconstructive Surgery: January 2010 - Volume 125 - Issue 1 - p 378-383 doi: 10.1097/PRS.0b013e3181c2a571
[4] Gehring W. Nicotinic acid/niacinamide and the skin. J Cosmet Dermatol. 2004 Apr;3(2):88-93. doi: 10.1111/j.1473-2130.2004.00115.x. PMID: 17147561.
[5] Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation:
[6] Lee YI, Lee SG, Jung I, Suk J, Lee MH, Kim DU, Lee JH. Effect of a Topical Collagen Tripeptide on Antiaging and Inhibition of Glycation of the Skin: A Pilot Study. Int J Mol Sci. 2022 Jan 20;23(3):1101. doi: 10.3390/ijms23031101. PMID: 35163025; PMCID: PMC8835374.
[7] Chen, H.J., Lee, P.Y., Chen, C.Y. et al. Moisture retention of glycerin solutions with various concentrations: a comparative study. Sci Rep 12, 10232 (2022).

**This is a subjective assessment based on the strength of the available informations and our estimation of efficacy.

*Result may vary. The information contained in this website is provided for general informational purpose. No medical claims are implied in this content, and the information herein is not intended to be used for self diagnosis or self treatment of any condition.

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