Intraceuticals Atoxelene Daily Serum Reviews - Does It Work?

Intraceuticals Atoxelene Daily Serum works with the mechanism of reducing the appearance of the aging skin with long term and accumulative results. Read more!

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In This Review

Intraceuticals Atoxelene Daily Serum Overview

Atoxelene Serum is a known strength serum that is used to reduce the visible appearance of the skins, which are aging with results that are long term and accumulative. The product is manufactured with botanical peptide, which directly affects the expressions of the fine lines and the wrinkles on your face. The product thus works with the mechanism of reducing the appearance of the aging skin with long term and accumulative results. Using this product continuously ensures that you get sustainable results. It is a natural enhancer to more invasive treatments.

Atoxelene Serum usually targets the lines, which appear on the face after an expression such that it acts on the same lines instantly. The expression lines are found around the lips, eyes and the forehead. The lines are also located on the nasal curves caused by the face muscle contractions. It is packaged in a 30ml bottle, and it is sold at $149.

How Does It Rate?

Overall Rating: 3.5
intraceuticals atoxelene daily serumIntraceuticals Atoxelene Daily Serum


Value for Cost

3.5/5Value for Cost
Return Policy

3.5/5Return Policy


Brand Highlights

  • The manufacturer of Atoxelene Serum is Intraceuticals.
  • The manufacturer claims that the product targets your expression lines which are found around your eyes, lips, and forehead for instant and sustainable results which is visible.
  • According to the manufacturer, the product visibly lifts the brow as it plumps lip contour.
  • He states that once you use this product the fine lines and wrinkles around your eyes might dimish.


Beverly Hills MD Deep Wrinkle Filler

*All individuals are unique. Your results can and will vary.

Key Ingredients

  • Water
  • Squalane
  • Ethoxydiglycol
  • Ceteareth-20
  • cetyl Octapeptide-3
  • Hydrolyzed Hibiscus Extract
  • Hyaluronic
  • Dextran Sulfate
  • Hyaluronate
  • Serum Albumin
  • Dextrin
  • Hexane-diol
  • Panthenols
  • Caprylyls Glycol
  • Carbomers
  • Triethanolamine
  • Disodium.


  • It is helpful in targeting the expression lines for instant results which are sustainable.
  • It helps to smoothen the appearance of the wrinkles and the fine lines
  • It aids to lift the eyebrows and plump the lip contour


  • There are no cons on Atoxelene Serum

How Does it Work?

Intraceuticals' Atoxelene Daily Serum contains botanical peptides that target deep signs of ageing such as expression lines and deep wrinkles. Intraceuticals Atoxelene Daily Serum, an alternative to invasive treatments, is ideal for lines around the eyes, lips, and forehead, as well as lines around the mouth, visibly plumping areas of concern.

Intraceuticals Atoxelene Daily Serum Ingredients – Are they Safe & Effective?


- Water is an crucial ingredient which not only hydrated and refresh your body but also helps to maintain the elasticity of your skin. It provides a hydrating and lightweight texture to formulations. This water-based serum is designed to absorb easily into the skin, so the active ingredients can penetrate deeply and effectively. In our Wrinkle Repair Night Treatment Review article we mention presence of this ingredient which helps to keep skin hydrated and retain its elasticity.


- Squalane is a highly purified botanical lipid derived from sugar cane. Squalane is known for its ability to renew the skin's barrier and keep it smooth, supple, and moisturized. It has a strong affinity for the skin and absorbs quickly. [1]

Cetyl Octapeptide-3

- This is a peptide that fights wrinkles by penetrating deep into the skin. Studies have shown that Acetyl Octapeptide-3 improves the process of muscle contraction and skin tightening on your face.[2]


- This is used in skincare formulations due to its moisture-retaining properties. It has been shown in clinical trials to improve skin hydration levels by trapping and attracting moisture. It has also been linked to increased collagen production and quicker wound healing.[3]

Dextran Sulfate

- Dextran is a substance that attracts and binds moisture to your skin, resulting in smooth, youthful-looking skin. Dextran has been shown in studies to be effective in the treatment of severe burns.[4]


- This deeply hydrating ingredient moisturizes and conditions the brows and follicles, prevents dryness, and may plump and smooth fine lines around the brows. An article in Molecules looked at the benefits of combining hyaluronic acid with other bioactive ingredients in cosmeceuticals.[5]

Serum Albumin

- This is the most common protein found in human blood, and it transports free fatty acids with it. It provides protein to the skin.[6]


- Hexanediol is a preservative and humectant that can bind moisture. The transparent liquid of the ingredient acts as a solvent and aids in the dissolution of other materials.[7]

Other Ingredients
Carbomers, Caprylyls Glycol, Ethoxydiglycol, Ceteareth-20, Hydrolyzed Hibiscus Extract, Dextrin, Panthenols, Triethanolamine, and Disodium.

Atoxelene Serum Alternatives


drmtlgy needle

*All individuals are unique. Your results can and will vary.

Intraceuticals Atoxelene Daily Serum FAQ's

Q: Is there a particular diet to be followed?

A: There is no particular diet to stick to while using this supplement

Q: What are the possible side effects of this Intraceuticals Atoxelene Daily Serum?

A: There are no side effects associated with Atoxelene Serum.

Intraceuticals Atoxelene Daily Serum - Final Verdict

Most people always admire their skins to be smooth in nature. This is always never favored with the change in time because as time goes the more they become aged and wrinkles come in. That is why most people tend to get creams and serums that can revert their skin back to the youthful skin. You need to be very careful while purchasing the serums and supplements for your skin. The skin is the most sensitive part of the human body. Apply serum to the skin might cause the high negative impacts to the skin. You don't need to regret later after using this serum? Get to know the finer details about the product before you apply it on your body.

Atoxelene Serum is available on the official website. You don't need to rush to products, which you are not familiar with. Get the finer details of Atoxelene Serum as you make your decision. As we always say don’t get lured by the manufacturer’s claims. Make your own research find out the associated health conditions if any and then only commence the purchase the product.

There are several anti-wrinkle serum present in the current market such as Vibriance Super C Serum that helps to fade age spots and areas of discolouration and deeply hydrate the skin.

As we age the composition, texture and appearance of our skin changes. Signs of skin aging include wrinkles, fine lines, loss of moisture, uneven tone, and dull, tired-looking skin. There are countless anti-wrinkle creams on the market promising to make skin look and feel younger. Many anti-wrinkle creams promise everything short of a facelift or to provide the much sought after "fountain of youth". In reality most are just moisturizers marketed as anti-aging products.

Below you’ll find some of the most effective wrinkle serum/cream formulations on the market today, in our opinion.

Our Top Anti Wrinkle Serums Choices

Verdict on Claimed Benefits: Below is our summary of the available evidence for the claimed benefits of below mentioned anti-wrinkle serums based on the available research:

DRMTLGY Needless Serum | Organic Anti-Aging Skincare
Strengthens the Skin's Moisture Barrier*Gold Star Evidence
Targets the Appearance of Fine Lines & Wrinkles*Gold Star Evidence
Helps to Improve Skin Tone & Reduce the Dark Spots*Gold Star Evidence
Firms and Tightens the Skin, Improving Elasticity*Strong Evidence
Rating Breakdown
Support for Claims:
Ingredient Safety:
Value for the Price:
Brand Transparency:
Overall Rating: 4.9
Beverly Hill MD Wrinkle Repair Night Treatment | Overnight Repair Formula
Hydrates the Skin Overnight & Replenishes Moisture*Gold Star Evidence
Encourages Skin Cell Turnover and Renewal*Strong Evidence
Minimize the Appearance of Wrinkles & Promote Skin Renewal*Gold Star Evidence
Provides Skin Firmness and Elasticity*Strong Evidence
Rating Breakdown
Support for Claims:
Ingredient Safety:
Value for the Price:
Brand Transparency:
Overall Rating: 4.8
Beverly Hills MD Line Smoothing Serum
Reduce The Appearance of Fine Lines & Wrinkles*Gold Star Evidence
Support The Skin's Structural Foundation & Elasticity*Strong Evidence
Powerful Collagen-supporting Peptides Moisture-rich Volumizers*Strong Evidence
Promotes Youthful Skin*Strong Evidence
Rating Breakdown
Support for Claims:
Ingredient Safety:
Value for the Price:
Brand Transparency:
Overall Rating: 4.8

Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of Exclusive Best Offer. We do not verify or endorse any claims made in these reviews. Please read the full product reviews disclaimer. *All individuals are unique. Your results can and will vary.

Customer Reviews for Intraceuticals Atoxelene Daily Serum

Intraceuticals Atoxelene Daily Serum Reviews - Does It Work?

Customer Reviews & Ratings

1.0 out of 5

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  1. Fernanda Zubiria

    Intraceuticals Atoxelene Daily Serum is overpriced
    At $149 for 30ml, Intraceuticals Atoxelene Daily serum is grossly overpriced. I've been using it for almost three months and haven't noticed any significant changes in my skin. Definitely not worth the price.

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Intraceuticals Atoxelene Daily Serum
1.01 fl oz
Water, Squalane, Ethoxydiglycol, Ceteareth-20, Acetyl Octapeptide-3, Hydrolyzed Hibiscus Extract, Hyaluronic, Dextran Sulfate, Hyaluronate, Serum Albumin, Dextrin, Hexane-diol, Panthenols, Caprylyls Glycol, Carbomers, Triethanolamine and Disodium

7 Sources

We review published medical research in respected scientific journals to arrive at our conclusions about a product or health topic. This ensures the highest standard of scientific accuracy.

[1] Huang ZR, Lin YK, Fang JY. Biological and pharmacological activities of squalene and related compounds: potential uses in cosmetic dermatology. Molecules. 2009 Jan 23;14(1):540-54. doi: 10.3390/molecules14010540. PMID: 19169201; PMCID: PMC6253993.
[2] Ji, M., Lee, HS., Kim, Y. et al. Method development for acetyl octapeptide-3 analysis by liquid chromatography-tandem mass spectrometry. J Anal Sci Technol 11, 34 (2020).
[3] Draelos, Z.D., Diaz, I., Namkoong, J. et al. Efficacy Evaluation of a Topical Hyaluronic Acid Serum in Facial Photoaging. Dermatol Ther (Heidelb) 11, 1385–1394 (2021).
[4] Lu G, Rausell-Palamos F, Zhang J, Zheng Z, Zhang T, Valle S, Rosselot C, Berrouet C, Conde P, Spindler MP, Graham JG, Homann D, Garcia-Ocaña A. Dextran Sulfate Protects Pancreatic ?-Cells, Reduces Autoimmunity, and Ameliorates Type 1 Diabetes. Diabetes. 2020 Aug;69(8):1692-1707. doi: 10.2337/db19-0725. Epub 2020 May 7. PMID: 32381645; PMCID: PMC7372066.
[5] Anti-Skin-Aging Effect of a Treatment with a Cosmetic Product and a Food Supplement Based on a New Hyaluronan: A Randomized Clinical Study in Healthy Women:
[6] Effect of Bovine Serum Albumin Treatment on the Aging and Activity of Antibodies in Paper Diagnostics:
[7] Ganceviciene R, Liakou AI, Theodoridis A, Makrantonaki E, Zouboulis CC. Skin anti-aging strategies. Dermatoendocrinol. 2012 Jul 1;4(3):308-19. doi: 10.4161/derm.22804. PMID: 23467476; PMCID: PMC3583892.

**This is a subjective assessment based on the strength of the available informations and our estimation of efficacy.

*Result may vary. The information contained in this website is provided for general informational purpose. No medical claims are implied in this content, and the information herein is not intended to be used for self diagnosis or self treatment of any condition.

*Disclosure of Material connection: Some of the links in the post above are "associate sales links." This means if you can click on the link and purchase an item, we will receive a commission. Regardless, we only recommend products or services which we use personally and/or believe will add value to our readers. We are disclosing this in accordance with the Federal Trade Commission's 16 CFR, Part 255: "Guides Concerning the Use of Endorsements and Testimonials."

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