SkinCeuticals Triple Lipid Restore 2:4:2 Reviews - Is It Safe?

SkinCeuticals Triple Lipid Restore 2:4:2 is an anti-aging cream manufactured by company SkinCeuticals that improve skin appearance, texture, and radiance.

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In This Review

Overview - SkinCeuticals Triple Lipid Restore 2:4:2

SkinCeuticals Triple Lipid Restore 2:4:2 is a patented anti-aging cream that claims to refill cellular lipids while nourishing dry skin. It contains the optimal lipid ratio of 2% pure ceramides, 4% natural cholesterol, and 2% fatty acids hence the ratio is 2:4:2.

With cholesterol being the dominant component, this cream may restore the skin’s external barrier, support natural self-repair, and nourish the skin with essential anti-aging ingredients[1].

According to the manufacturer, the use of this product improves skin evenness. It may result in skin smoothness, laxity, improved pore size, and enhanced skin radiance. It may help restore ceramides, natural cholesterol, balanced fatty acids, reduce skin dryness as well as provides a unique lipid stabilization system

How Does It Rate?

Overall Rating: 3.5
SkinCeuticals Triple Lipid Restore 2:4:2SkinCeuticals Triple Lipid Restore 2:4:2


Value For Cost

3.5/5Value For Cost
Return Policy

3.5/5Return Policy


Brand Highlights

  • SkinCeuticals Triple Lipid Restore 2:4:2 is a product manufactured by the SkinCeuticals Company.
  • SkinCeuticals is able to create products with ingredients that are supported by science thanks to research and innovation.


Beverly Hills MD Deep Wrinkle Filler

*All individuals are unique. Your results can and will vary.

Key Ingredients

  • Ceramides 1 and 3
  • Natural Cholesterol
  • Fatty Acids
  • Essential Oils


  • It may improve skin appearance, texture, laxity, pores, and radiance
  • This product contains natural lipids that supplement the skin’s lipid
  • SkinCeuticals Triple Lipid Restore 2:4:2 is suitable for all skin types
  • This cream does not contain parabens and dyes thus may not cause skin irritation
  • May not cause any side effects to users


  • The product does not come with a free sample for trial before use
  • It may not be a stand-alone product and thus may require users to invest in other products to establish a skincare routine

Who is the Manufacturer of SkinCeuticals Triple Lipid Restore 2:4:2?

The manufacturer of this anti-wrinkle cream is SkinCeuticals, a company that sells a wide range of skin products in the USA. The company claims to design all its products focused on skin health. Using research and innovation, SkinCeuticals is able to formulate products using ingredients that are backed by science. The company’s philosophy is guided by three pillars which are to prevent, protect, and correct skin issues for its international client base.

How Does SkinCeuticals Triple Lipid Restore 2:4:2 Work?

As we had explained earlier, SkinCeuticals Triple Lipid Restore 2:4:2 is composed of ceramides, natural cholesterol, and fatty acids which work to supplement the skin’s lipid levels. With this extra nourishment, the skin’s external barrier is restored, skin firmness is improved, large pores are reduced, and in the process, the skin’s volume and radiance are enhanced. In an 8-week study, SkinCeuticals Triple Lipid Restore 2:4:2, the following results were concluded;

  • 66% improvement in smoothness
  • 44% improvement in pore appearance
  • 35% improvement in laxity
  • 26% improvement in radiance
  • 20% improvement in evenness

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SkinCeuticals Triple Lipid Restore 2:4:2 Ingredients – Are they Safe & Effective?

Ceramides 1 and 3 -

Ceramides are a family of waxy lipid molecules that are claimed to form a protective layer to prevent the skin from damage and environmental stressors. According to the Clinical, Cosmetic, and Investigational Dermatology, ceramides were found to increase skin hydration and improve barrier function[2].

Natural Cholesterol -

Along with ceramides and fatty acids, cholesterol improves the water barrier formation on the skin according to the Indian Journal of Dermatology. In topical creams, cholesterol and ceramides help to improve the skin texture making it softer and smoother[3].

Fatty Acids -

These are components found in botanical oils. The composition of human skin lipids contains triacylglycerols and free fatty acids. According to Frontiers in Pharmacology, fatty acids are naturally present in the human stratum corneum[4]. The journal further points out that the oiliness of the skin correlates with the level of fatty acids.

Essential Oils -

This product contains a blend of lavender, rosemary, and peppermint oil. These oils are used for medical purposes especially for dermatological uses as per the Evidence Based Complimentary and Alternative Medicine. Essential oils have antimicrobial properties against pathogens that cause dermatological infections[5].



*All individuals are unique. Your results can and will vary.

SkinCeuticals Triple Lipid Restore 2:4:2 - FAQ’s

Q: How Should You Use SkinCeuticals Triple Lipid Restore 2:4:2?

A: Take a small amount of the cream between fingertips, warm, and apply to face, neck, and chest in circular motions. Apply once or twice daily. If using in the morning, apply after a SkinCeuticals vitamin C antioxidant serum and before SkinCeuticals sunscreen. At night, apply after retinol application.

Q: How Much Does SkinCeuticals Triple Lipid Restore 2:4:2 Cost?

A: This cream is quite costly as it costs $128.00 for the 1.6 fl oz tub.

Q: What is SkinCeuticals Triple Lipid Restore 2:4:2 Return Policy?

A: SkinCeuticals offer a 30 day return policy for all products bought via the company’s official website. Unsatisfied buyers can return unopened products within 30 days of the purchase date.

Q: Does SkinCeuticals Triple Lipid Restore 2:4:2 Offer a Free Trial?

A: No, there are no free trials provided for this anti-aging cream at the moment. However, at the reviews section, some customers shared that they had received samples from the brand, suggesting a repeat offer of the same may happen in the future as an advertising strategy.


Beverly Hills MD Deep Wrinkle Filler

*All individuals are unique. Your results can and will vary.

SkinCeuticals Triple Lipid Restore 2:4:2 – Final Verdict

SkinCeuticals Triple Lipid Restore 2:4:2 is an anti-aging cream that claims to supplement the skin’s lipid level through its ceramides, cholesterol, and fatty acids content. These ingredients help improve the skin’s epidermal function thus preventing hydration loss thus preventing skin dryness. With it, the skin is able to retain its laxity, smoothness, and radiance[6].

Out of the 668 reviews on SkinCeuticals official website, this product scored 4.7 stars which simply means, users loved it! Among its notable strengths include the fact that it leaves the skin hydrated, smooth, and supple. The cream is lightweight and absorbs fast, meaning the results also become noticeable fast. The maker points that this lipid restoring cream was awarded the 2020 InStyle Best Beauty Buys.

In overview, it is safe to say that with all the shared details about this cream, it may be worth the attention and a try. Regarding its long-term use and how safe it is, there might not be a cause to worry as it is said to be side effect free.

Not to mention that it can be used alongside your other skincare routine, unlike some products which don’t allow mixing their creams with other products.

As we age the composition, texture and appearance of our skin changes. Signs of skin aging include wrinkles, fine lines, loss of moisture, uneven tone and dull, tired-looking skin. There are countless anti-wrinkle creams on the market promising to make skin look and feel younger. Many anti-wrinkle creams promise everything short of a facelift or to provide the much sought after "fountain of youth". In reality most are just moisturizers marketed as anti-aging products.

Below you'll find some of the most effective wrinkle serum/cream formulations on the market today, in our opinion.

Our Top Anti Aging Choices

Verdict on Claimed Benefits: Below is our summary of the available evidence for the claimed benefits of below mentioned anti-aging products and anti-wrinkle creams based on the available research:

Deep Wrinkle Filler | Anti-aging Skin Care Formula
Erase The Appearance Of Fine Lines*Gold Star Evidence
Fill in Deep Wrinkles*Gold Star Evidence
Give Skin a Smoother, More Flawless Appearance*Gold Star Evidence
Nourishes Skin For Lasting Results*Strong Evidence
Rating Breakdown
Support for Claims:
Ingredient Safety:
Value for the Price:
Brand Transparency:
Overall Rating: 4.9
Beverly Hills MD Dermal Repair Complex | Best Anti-Aging Supplement
Diminishes Wrinkles & Dullness*Gold Star Evidence
Reduces Sagging or Drooping*Gold Star Evidence
Improves Hair & Nails Strength*Strong Evidence
Enhances Skin Elasticity*Gold Star Evidence
Rating Breakdown
Support for Claims:
Ingredient Safety:
Value for the Price:
Brand Transparency:
Overall Rating: 4.9
XYZ Smart Collagen | The Best Anti-aging Cream
Wrinkles Reduction*Gold Star Evidence
Improves Skin Firmness*Gold Star Evidence
Improves Skin Texture*Strong Evidence
Smart Collagen Management*Strong Evidence
Rating Breakdown
Support for Claims:
Ingredient Safety:
Value for the Price:
Brand Transparency:
Overall Rating: 4.7
Hydrossential Serum | All-Natural Skin Care Product
Support Skin Health*Gold Star Evidence
Helps Eliminate Acne, Dark Spots, Fine Lines*Strong Evidence
Improves Resistance to Inflammation*Gold Star Evidence
Repair and Restore Damaged Skin Cells*Strong Evidence
Rating Breakdown
Support for Claims:
Ingredient Safety:
Value for the Price:
Brand Transparency:
Overall Rating: 4.7

Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of Exclusive Best Offer. We do not verify or endorse any claims made in these reviews. Please read the full product reviews disclaimer. *All individuals are unique. Your results can and will vary.

Customer Reviews for Skinceuticals Lipid Restore 2:4:2

SkinCeuticals Triple Lipid Restore 2:4:2 Reviews - Is It Safe?

Customer Reviews & Ratings

5.0 out of 5

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  1. Julia W.

    Love the way it feels on my skin.
    After using this anti-wrinkle skin cream for over 3 months, I do feel my skin has definitely firmed and wrinkles are less noticeable. I use to smoke a lot and have been quite surprised how the lines above my lip have decreased. I have extremely dry skin and have found that this keeps my face feeling moisturized now. I don't need to apply extra moisturizer on my face now. Skinceuticals Lipid Restore 2:4:2 does what it claims!
  2. Katherine Keter

    My daughter recommended Skinceuticals Lipid Restore 2:4:2
    I started using Skinceuticals Lipid Restore 2:4:2 two months ago after my daughter recommended it to me. The product has worked perfectly for her. Since we have similar skin types, we figured that it might work well for me too. I am extremely impressed by how my skin feels now. I think at first I expected that the product would sting, but I haven't had that effect. I hate it when I have heavy ingredients on my skin because they make it feel uncomfortable. Skinceuticals Lipid Restore 2:4:2 is very light and doesn't irritate at all. I have only used it for 10 weeks and my skin already feels softer and more hydrated. I believe that I will experience even better results if I continue using Skinceuticals Lipid Restore 2:4:2.
  3. Kennedy Clark

    Works well for my dry skin
    I have always had dry skin, and finding products that would work well for my skin type wasn't the easiest thing. Lately, I discovered Skinceuticals Lipid Restore 2:4:2 and I am pleased with the results. Skinceuticals Lipid Restore 2:4:2 is an anti-aging product that slows down the signs of aging by giving the user a rejuvenated look. It's been twelve weeks since I started using Skinceuticals Lipid Restore 2:4:2 and it hasn't irritated my skin at all. I don't get the dry or red patches that other products usually leave on the skin. I am also realizing huge benefits with regards to how my skin feels. I usually apply the serum after exfoliating and it leaves my skin glowing and illuminating. I actually don't need to wear makeup nowadays.
  4. Rachel Putilova

    Works amazingly well, highly recommended
    I was kinda deceptive about using it, but I would say this is a magic cream it works amazingly on my skin I can feel the texture no mess using my fingers so easy to apply, something that I really like’s that it doesn’t have any fragrance that irritates my skin since the first time I used it I saw the results it plumped my wrinkles and my skin feels super smooth.
  5. Rachel M.

    This stuff is perfect!
    Finally, a cream that does exactly what it says!! I love how I can wear it without putting makeup on and it makes me look fresh. And when I do wear makeup it makes my concealer go on smooth!
  6. Kay Nelson

    Really nice cream
    I found this cream to be very helpful in my attempt to get rid of fine lines & wrinkles. For the few days of use that I had with my free sample, I was very pleased with the results. Thank you for letting me have a chance to try this.

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Skinceuticals Lipid Restore 2:4:2
Skin Ceuticals
48 ml
Ceramides 1 and 3, Natural Cholesterol, Fatty Acids,and Essential Oils.

6 Sources

We review published medical research in respected scientific journals to arrive at our conclusions about a product or health topic. This ensures the highest standard of scientific accuracy.

[1] Skin barrier function :
[2] Skin hydration is significantly increased by a cream formulated to mimic the skin’s own natural moisturizing systems :
[3] Moisturizers: The slippery road :;year=2016;volume=61;issue=3;spage=279;epage=287;aulast=Sethi
[4] The Enigma of Bioactivity and Toxicity of Botanical Oils for Skin Care :
[5] Commercial Essential Oils as Potential Antimicrobials to Treat Skin Diseases :
[6] Repair and Maintenance of the Epidermal Barrier in Patients Diagnosed with Atopic Dermatitis :

**This is a subjective assessment based on the strength of the available informations and our estimation of efficacy.

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